C0000098 - An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to PARAQUAT, has also been used as an herbicide.

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Lang Dictionary CODE			LUI	preferred no	SUI	preference Yes / No	Terms, descriptions
							CUI C0000098

Russian	Medical Subject Headings Russian	D015655	L3334704	preferred	S3862229	Y	1-МЕТИЛ-4-ФЕНИЛПИРИДИНИЙ
Russian	Medical Subject Headings Russian	D015655	L0889254	no	S1093071	Y	1-METIL-4-FENILPIRIDINII
Russian	Medical Subject Headings Russian	D015655	L1546612	no	S1842521	Y	TSIPERKVAT
Russian	Medical Subject Headings Russian	D015655	L3376316	no	S3903809	Y	ЦИПЕРКВАТ
	Medical Subject Headings				A0016589	AT38133955	An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to PARAQUAT, has also been used as an herbicide.