C0000248 - A synthetic, light tan crystalline solid that is insoluble in water and soluble in alcohols, glycols, ether, acetic acid, and fat solvents. It is used as a positive control by toxicologists to study the carcinogenicity and mutagenicity of aromatic amines. When heated to decomposition, 2-acetylaminofluorene emits toxic fumes of nitrogen oxides. The primary routes of potential human exposure to 2-acetylaminofluorene are inhalation and dermal contact. It is reasonably anticipated to be a human carcinogen. (NCI05) 1/10
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Terms, descriptions
CUI    C0000248
RussianMedical Subject Headings Russian D015073 L3334797preferred S3862303 Y 2-АЦЕТИЛАМИНОФЛУОРЕН
RussianMedical Subject Headings Russian D015073 L0889285no S1093102 Y 2-ATSETILAMINOFLUOREN
RussianMedical Subject Headings Russian D015073 L1507109no S1803018 Y 2-ATSETAMIDOFLUOREN
RussianMedical Subject Headings Russian D015073 L1519958no S1815867 Y FLUORENIL-2-ATSETAMID
RussianMedical Subject Headings Russian D015073 L3334796no S3862302 Y 2-АЦЕТАМИДОФЛУОРЕН
RussianMedical Subject Headings Russian D015073 L3374432no S3901925 Y ФЛУОРЕНИЛ-2-АЦЕТАМИД
Medical Subject Headings A0016881 AT43116097 A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
NCI Thesaurus A7568439 AT197967317 A synthetic, light tan crystalline solid that is insoluble in water and soluble in alcohols, glycols, ether, acetic acid, and fat solvents. It is used as a positive control by toxicologists to study the carcinogenicity and mutagenicity of aromatic amines. When heated to decomposition, 2-acetylaminofluorene emits toxic fumes of nitrogen oxides. The primary routes of potential human exposure to 2-acetylaminofluorene are inhalation and dermal contact. It is reasonably anticipated to be a human carcinogen. (NCI05)