C0000340 - A mitochondrial cytochrome P450 enzyme that catalyzes the 1-alpha-hydroxylation of 25-hydroxyvitamin D3 (also known as 25-hydroxycholecalciferol) in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP27B1 gene, converts 25-hydroxyvitamin D3 to 1-alpha,25-dihydroxyvitamin D3 which is the active form of VITAMIN D in regulating bone growth and calcium metabolism. This enzyme is also active on plant 25-hydroxyvitamin D2 (ergocalciferol).

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Lang Dictionary CODE			LUI	preferred no	SUI	preference Yes / No	Terms, descriptions
							CUI C0000340

Russian	Medical Subject Headings Russian	D015090	L3334849	preferred	S3862281	Y	25-ГИДРОКСИХОЛЕКАЛЬЦИФЕРОЛ-1-ГИДРОКСИЛАЗА
Russian	Medical Subject Headings Russian	D015090	L0889298	no	S1093115	Y	25-GIDROKSIKHOLEKAL'TSIFEROL-1-GIDROKSILAZA
Russian	Medical Subject Headings Russian	D015090	L2392459	no	S2828455	Y	25-GIDROKSIVITAMIN D3 1-AL'FA-GIDROKSILAZA
Russian	Medical Subject Headings Russian	D015090	L3334847	no	S3862279	Y	25-ГИДРОКСИВИТАМИН D3 1-АЛЬФА-ГИДРОКСИЛАЗА
	Medical Subject Headings				A2362043	AT38135392	A mitochondrial cytochrome P450 enzyme that catalyzes the 1-alpha-hydroxylation of 25-hydroxyvitamin D3 (also known as 25-hydroxycholecalciferol) in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP27B1 gene, converts 25-hydroxyvitamin D3 to 1-alpha,25-dihydroxyvitamin D3 which is the active form of VITAMIN D in regulating bone growth and calcium metabolism. This enzyme is also active on plant 25-hydroxyvitamin D2 (ergocalciferol).