C0000578 - An aromatic amino acid with antidepressant activity. In vivo, oxitriptan (or 5-hydroxytryptophan) is converted into 5-hydroxytryptamine (5-HT or serotonin) as well as other neurotransmitters. Oxitriptan may exert its antidepressant activity via conversion to serotonin or directly by binding to serotonin (5-HT) receptors within the central nervous system (CNS). Endogenous oxitriptan is produced from the essential amino acid L-tryptophan. The exogenous therapeutic form is isolated from the seeds of the African plant Griffonia simplicifolia. 2/10
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Terms, descriptions
CUI    C0000578
RussianMedical Subject Headings Russian D006916 L3334975preferred S3862455 Y 5-ГИДРОКСИТРИПТОФАН
RussianMedical Subject Headings Russian D006916 L0889335no S1093152 Y 5-GIDROKSITRIPTOFAN
RussianMedical Subject Headings Russian D006916 L1507279no S1803188 Y 5-NTR
RussianMedical Subject Headings Russian D006916 L1507282no S1803191 Y 5-OKSITRIPTOFAN
RussianMedical Subject Headings Russian D006916 L1521565no S1817474 Y GIDROKSITRIPTOFAN
RussianMedical Subject Headings Russian D006916 L3334983no S3862465 Y 5-НТР
RussianMedical Subject Headings Russian D006916 L3334986no S3862469 Y 5-ОКСИТРИПТОФАН
RussianMedical Subject Headings Russian D006916 L3345063no S3872541 Y ГИДРОКСИТРИПТОФАН
Medical Subject Headings A0017424 AT64676714 The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
(CPTSP) CRISP Thesaurus A0384334 AT51220313 precursor of serotonin used as antiepileptic and antidepressant.
PDQ A11915396 AT70653188 An aromatic amino acid with antidepressant activity. In vivo, 5-hydroxytryptophan (5-HTP) is converted into 5-hydroxytryptamine (5-HT or serotonin) as well as other neurotransmitters. 5-HTP may exert its antidepressant activity via conversion to serotonin or directly by binding to serotonin (5-HT) receptors within the central nervous system (CNS). Endogenous 5-HTP is produced from the essential amino acid L-tryptophan. Exogenous therapeutic 5-HTP is isolated from the seeds of the African plant Griffonia simplicifolia. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=459776&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=459776&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C52181" NCI Thesaurus)
NCI Thesaurus A15558691 AT198130390 An aromatic amino acid with antidepressant activity. In vivo, oxitriptan (or 5-hydroxytryptophan) is converted into 5-hydroxytryptamine (5-HT or serotonin) as well as other neurotransmitters. Oxitriptan may exert its antidepressant activity via conversion to serotonin or directly by binding to serotonin (5-HT) receptors within the central nervous system (CNS). Endogenous oxitriptan is produced from the essential amino acid L-tryptophan. The exogenous therapeutic form is isolated from the seeds of the African plant Griffonia simplicifolia.