C0001259 - A chromopeptide antineoplastic antibiotic isolated from the bacterial genus Streptomyces. Actinomycin antibiotics inhibit DNA replication and RNA and protein synthesis by various mechanisms such as intercalating into the minor groove of DNA and interfering with the function of topoisomerase II. 1/10
home    UMLS 2020

293,031 терминов и синонимов из MeSH и LOINC

Поиск по CUI
Поиск по CODE


Поиск по одному или нескольким словам или частям слов
   


Lang   Dictionary       CODE         LUI      
preferred
no
        SUI   preference
Yes / No
Terms, descriptions
CUI    C0001259
(CPTSP) CRISP Thesaurus A0472784 AT51220162 group of peptide antibiotic agents, isolated from several species of Streptomyces (originally Actinomyces), that are active against gram positive bacteria, fungi, and neoplasms; they form complexes with DNA and therefore inhibit RNA synthesis, primarily the ribosomal type.
NCI Thesaurus A15556794 AT198102377 A chromopeptide antineoplastic antibiotic isolated from the bacterial genus Streptomyces. Actinomycin antibiotics inhibit DNA replication and RNA and protein synthesis by various mechanisms such as intercalating into the minor groove of DNA and interfering with the function of topoisomerase II.