C0002026 - A synthetic short-acting opioid with analgesic and local anesthesia enhancing activity. Alfentanil primarily binds to mu-opioid receptor, a G-protein-coupled receptor, thereby mimicking the actions of morphine, the prototypical mu receptor agonist. This agent induces anti-nociception responses mediated through inhibiting the release of various neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline; in addition, the release of vasopressin, somatostatin, insulin and glucagon are also inhibited. 1/10
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Terms, descriptions
CUI    C0002026
RussianMedical Subject Headings Russian D015760 L3337684preferred S3865165 Y АЛФЕНТАНИЛ
RussianMedical Subject Headings Russian D015760 L0889711no S1093528 Y ALFENTANIL
RussianMedical Subject Headings Russian D015760 L1508069no S1803978 Y AL'FENTANIL
RussianMedical Subject Headings Russian D015760 L3337869no S3865350 Y АЛЬФЕНТАНИЛ
Medical Subject Headings A0021528 AT38150038 A short-acting opioid anesthetic and analgesic derivative of FENTANYL. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
NCI Thesaurus A12804691 AT197983288 A synthetic short-acting opioid with analgesic and local anesthesia enhancing activity. Alfentanil primarily binds to mu-opioid receptor, a G-protein-coupled receptor, thereby mimicking the actions of morphine, the prototypical mu receptor agonist. This agent induces anti-nociception responses mediated through inhibiting the release of various neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline; in addition, the release of vasopressin, somatostatin, insulin and glucagon are also inhibited.