C0002073 - A type of drug that is used in the treatment of cancer. It interferes with the cell's DNA and inhibits cancer cell growth. 3/10
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Terms, descriptions
CUI    C0002073
RussianMedical Subject Headings Russian D000477 L3337570preferred S3865051 Y АЛКИЛИРУЮЩИЕ СРЕДСТВА
RussianMedical Subject Headings Russian D000477 L0889733no S1093550 Y ALKILIRUIUSHCHIE SREDSTVA
Medical Subject Headings A0021640 AT38144042 Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.
(CPTSP) CRISP Thesaurus A0318310 AT51219635 chemical agent that can add alkyl groups (for example, ethyl or methyl groups) to another molecule; many mutagens act through alkylation.
MSHNOR A26521873 AT211599800 Meget reaktive stoffer som innfører alkylradikaler i biologisk aktive molekyler og derved hindrer deres normale funksjon. Mange blir brukt som antineoplastiske midler, men de fleste er sterkt toksiske, karsinogene, mutagene, teratogene og har immundempende effekter. De har også blitt brukt som komponenter i giftgasser.
NCI Thesaurus A7660487 AT198016373 Agents that replace hydrogen atom(s) in biologically active molecules with alky radical(s), hindering proper function. Alkylating agents exhibit cytotoxic effects through the alkylation of DNA, resulting in strand cross-linking, ultimately inhibiting DNA replication and cell growth.
NCI NCI Dictionary of Cancer Terms A7660487 AT198077895 A type of drug that is used in the treatment of cancer. It interferes with the cell's DNA and inhibits cancer cell growth.