C0002335 - The naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Alprostadil is a potent vasodilator agent that increases peripheral blood flow, inhibits platelet aggregation, and induces bronchodilation. Used in the treatment of erectile dysfunction, this agent produces corporal smooth muscle relaxation by binding to PGE receptors, resulting in the activation of adenylate cyclase and the subsequent accumulation of 3'5'-cAMP.

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Lang Dictionary CODE			LUI	preferred no	SUI	preference Yes / No	Terms, descriptions
							CUI C0002335

Russian	Medical Subject Headings Russian	D000527	L3337758	preferred	S3865239	Y	АЛЬПРОСТАДИЛ
Russian	Medical Subject Headings Russian	D000527	L0889682	no	S1093499	Y	AL'PROSTADIL
Russian	Medical Subject Headings Russian	D000527	L1536109	no	S1832018	Y	PGE1
Russian	Medical Subject Headings Russian	D000527	L1537490	no	S1833399	Y	PROSTAGLANDIN E1
Russian	Medical Subject Headings Russian	D000527	L3365525	no	S3893010	Y	ПРОСТАГЛАНДИН E1
	Medical Subject Headings				A0022197	AT115062597	A potent vasodilator agent that increases peripheral blood flow.
	PDQ				A11914790	AT70661484	The naturally occuring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Alprostadil is a potent vasodilator agent that increases peripheral blood flow, inhibits platelet aggregation, and induces bronchodilation. Used in the treatment of erectile dysfunction, this agent produces corporal smooth muscle relaxation by binding to PGE receptors, resulting in the activation of adenylate cyclase and the subsequent accumulation of 3'5'-cAMP. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=360459&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=360459&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C28816" NCI Thesaurus)
	Medical Subject Headings Czech				A13057362	AT231386678	Vazodilatans, prostaglandin E1. Používá se např. k léčbě ICHDK a poruch erekce. Léky: Caverject, Prostavasin, Prostin. (cit. Velký lékařský slovník online, 2017 http://lekarske.slovniky.cz)
	NCI NCI Dictionary of Cancer Terms				A7568662	AT197967081	A drug that is used to treat impotence (inability to have an erection) and is being studied in the treatment of sexual problems in men who have had surgery for prostate cancer. It is a type of vasodilator.
	NCI Thesaurus				A7568662	AT205727022	The naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Alprostadil is a potent vasodilator agent that increases peripheral blood flow, inhibits platelet aggregation, and induces bronchodilation. Used in the treatment of erectile dysfunction, this agent produces corporal smooth muscle relaxation by binding to PGE receptors, resulting in the activation of adenylate cyclase and the subsequent accumulation of 3'5'-cAMP.