C0002436 - The pivoxil ester form of a semisynthetic, broad spectrum beta-lactam penicillin with antibacterial activity. Amdinocillin specifically binds to and inactivates penicillin-binding protein 2 (PBP 2) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis. 2/10
home    UMLS 2020

293,031 терминов и синонимов из MeSH и LOINC

Поиск по CUI
Поиск по CODE


Поиск по одному или нескольким словам или частям слов
   


Lang   Dictionary       CODE         LUI      
preferred
no
        SUI   preference
Yes / No
Terms, descriptions
CUI    C0002436
RussianMedical Subject Headings Russian D000561 L3337918preferred S3865399 Y АМДИНОЦИЛЛИН ПИВОКСИЛ
RussianMedical Subject Headings Russian D000561 L0889793no S1093610 Y AMDINOTSILLIN PIVOKSIL
RussianMedical Subject Headings Russian D000561 L1519881no S1815790 Y FL 1039
RussianMedical Subject Headings Russian D000561 L1536339no S1832248 Y PIVMETSILLINAM
RussianMedical Subject Headings Russian D000561 L3363214no S3890696 Y ПИВМЕЦИЛЛИНАМ
Medical Subject Headings A0022460 AT38133206 Pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin.
NCI Thesaurus A16756734 AT198096248 The pivoxil ester form of a semisynthetic, broad spectrum beta-lactam penicillin with antibacterial activity. Amdinocillin specifically binds to and inactivates penicillin-binding protein 2 (PBP 2) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.