C0002680 - A broad-spectrum, semi-synthetic, beta-lactam penicillin antibiotic with bactericidal activity. Ampicillin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis. Ampicillin is stable against hydrolysis by a variety of beta-lactamases, therefore, can be used in wide range of gram-positive and -negative infections. 2/10
home    UMLS 2020

293,031 терминов и синонимов из MeSH и LOINC

Поиск по CUI
Поиск по CODE


Поиск по одному или нескольким словам или частям слов
   


Lang   Dictionary       CODE         LUI      
preferred
no
        SUI   preference
Yes / No
Terms, descriptions
CUI    C0002680
RussianMedical Subject Headings Russian D000667 L3338213preferred S3865694 Y АМПИЦИЛЛИН
RussianMedical Subject Headings Russian D000667 L0889921no S1093738 Y AMPITSILLIN
RussianMedical Subject Headings Russian D000667 L1535789no S1831698 Y PENITSILLIN, AMINOBENZIL
RussianMedical Subject Headings Russian D000667 L3362662no S3890148 Y ПЕНИЦИЛЛИН, АМИНОБЕНЗИЛ
Medical Subject Headings A0023118 AT38141324 Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
(CPTSP) CRISP Thesaurus A0473494 AT51221835 semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
NCI Thesaurus A7568705 AT198102589 A broad-spectrum, semi-synthetic, beta-lactam penicillin antibiotic with bactericidal activity. Ampicillin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis. Ampicillin is stable against hydrolysis by a variety of beta-lactamases, therefore, can be used in wide range of gram-positive and -negative infections.