C0002823 - A proteolytic enzyme and defibrinogenating agent derived from the venom of the Malayan pit viper, with profibrinolytic and anticoagulant activities. Upon administration, ancrod cleaves fibrinogen and releases A-fibrinopeptides. This inactivates fibrinogen and leads to a reduction in blood viscosity, increases blood flow and perfusion of the microcirculation. 2/10
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Terms, descriptions
CUI    C0002823
RussianMedical Subject Headings Russian D000721 L3339346preferred S3866828 Y АРВИН
RussianMedical Subject Headings Russian D000721 L0890497no S1094314 Y ARVIN
RussianMedical Subject Headings Russian D000721 L1508696no S1804605 Y ANKROD
RussianMedical Subject Headings Russian D000721 L15165072no S18431934 Y ARVIN IRC-50
RussianMedical Subject Headings Russian D000721 L15175796no S18459479 Y АРВИН IRC-50
RussianMedical Subject Headings Russian D000721 L3338625no S3866106 Y АНКРОД
Medical Subject Headings A0023562 AT38154510 An enzyme fraction from the venom of the Malayan pit viper, Agkistrodon rhodostoma. It catalyzes the hydrolysis of a number of amino acid esters and a limited proteolysis of fibrinogen. It is used clinically to produce controlled defibrination in patients requiring anticoagulant therapy. EC 3.4.21.-.
NCI Thesaurus A19033467 AT198136067 A proteolytic enzyme and defibrinogenating agent derived from the venom of the Malayan pit viper, with profibrinolytic and anticoagulant activities. Upon administration, ancrod cleaves fibrinogen and releases A-fibrinopeptides. This inactivates fibrinogen and leads to a reduction in blood viscosity, increases blood flow and perfusion of the microcirculation.