C0004391 - The segregation and degradation of cytoplasmic constituents by AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer. 2/10
home    UMLS 2020

293,031 терминов и синонимов из MeSH и LOINC

Поиск по CUI
Поиск по CODE


Поиск по одному или нескольким словам или частям слов
   


Lang   Dictionary       CODE         LUI      
preferred
no
       SUI   preference
Yes / No
Terms, descriptions
CUI    C0004391
RussianMedical Subject Headings Russian D001343 L5696922preferred S6529959 Y АУТОФАГИЯ
RussianMedical Subject Headings Russian D001343 L0890677no S1094494 Y AUTOFAGOTSITOZ
RussianMedical Subject Headings Russian D001343 L3339870no S3867351 Y АУТОФАГОЦИТОЗ
RussianMedical Subject Headings Russian D001343 L6206010no S7120723 Y ПРОГРАМИРОВАННАЯ СМЕРТЬ КЛЕТКИ, ТИП II
RussianMedical Subject Headings Russian D001343 L6965948no S8109295 Y PROGRAMIROVANNAIA SMERT' KLETKI, TIP II
RussianMedical Subject Headings Russian D001343 L6967411no S8105207 Y AUTOFAGIIA
(CPTSP) CRISP Thesaurus A0318424 AT51223190 segregation of part of the cell's own cytoplasmic material within a membrane and its digestion after fusion of the segregated vacuole with a lysosome.
Gene Ontology A11626312 AT235088541 The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. [GOC:autophagy, ISBN:0198547684, PMID:11099404, PMID:9412464]
NCI NCI Dictionary of Cancer Terms A15566811 AT197959554 A normal process in which a cell destroys proteins and other substances in its cytoplasm (the fluid inside the cell membrane but outside the nucleus), which may lead to cell death. Autophagy may prevent normal cells from developing into cancer cells, but it may also protect cancer cells by destroying anticancer drugs or substances taken up by them.
NCI Thesaurus A15566811 AT197959555 Autophagy is a biological process that involves the lysosomal degradation of intracellular components using it a cell's own machinery. This process can play a role in cellular defense, embryonic development, and cell growth.
Medical Subject Headings A8406015 AT218105794 The segregation and degradation of cytoplasmic constituents by AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer.