293,031 терминов и синонимов из MeSH и LOINC
| Lang Dictionary CODE | LUI | preferred no |
SUI | preference Yes / No |
Terms, descriptions |
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| CUI C0004475 | |||||||
| Russian | Medical Subject Headings Russian | D001374 | L3337265 | preferred | S3864746 | Y | АЗАЦИТИДИН |
| Russian | Medical Subject Headings Russian | D001374 | L0890719 | no | S1094536 | Y | AZATSITIDIN |
| Medical Subject Headings | A0028304 | AT38134884 | A pyrimidine analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primarily into RNA. Azacytidine has been used as an antineoplastic agent. | ||||
| (CPTSP) CRISP Thesaurus | A0474272 | AT51219551 | pyrimidine analog that inhibits DNA methyltransferase, impairing DNA methylation, also an antimetabolite of cytidine, incorporated primarily into RNA; has been used as an antineoplastic agent. | ||||
| PDQ | A4343560 | AT70648911 | A pyrimidine nucleoside analogue of cytidine with antineoplastic activity. Azacitidine is incorporated into DNA, where it reversibly inhibits DNA methyltransferase, thereby blocking DNA methylation. Hypomethylation of DNA by azacitidine may activate tumor suppressor genes silenced by hypermethylation, resulting in an antitumor effect. This agent is also incorporated into RNA, thereby disrupting normal RNA function and impairing tRNA cytosine-5-methyltransferase activity. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39153&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39153&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C288" NCI Thesaurus) | ||||
| NCI Thesaurus | A7568968 | AT198029457 | A pyrimidine nucleoside analogue of cytidine with antineoplastic activity. Azacitidine is incorporated into DNA, where it reversibly inhibits DNA methyltransferase, thereby blocking DNA methylation. Hypomethylation of DNA by azacitidine may activate tumor suppressor genes silenced by hypermethylation, resulting in an antitumor effect. This agent is also incorporated into RNA, thereby disrupting normal RNA function and impairing tRNA cytosine-5-methyltransferase activity. (NCI04) | ||||
| NCI NCI Dictionary of Cancer Terms | A7568968 | AT198090646 | A drug that is used to treat myelodysplastic syndromes and is being studied in the treatment of other types of cancer. It belongs to the family of drugs called antimetabolites. | ||||
