C0006462 - An anxiolytic agent chemically and pharmacologically unrelated to benzodiazepines, barbiturates, or other sedative/hypnotic drugs. Although its exact mechanism of action is unknown, buspirone may exert its anti-anxiety effects via serotonin (5-HT1A) and dopamine receptors (D2) and may indirectly affect other neurotransmitter systems. Unlike typical benzodiazepine anxiolytics, this agent does not exert anticonvulsant or muscle relaxant effects and lacks prominent sedative effects. 1/10
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Terms, descriptions
CUI    C0006462
RussianMedical Subject Headings Russian D002065 L3342084preferred S3869566 Y БУСПИРОН
RussianMedical Subject Headings Russian D002065 L0891623no S1095440 Y BUSPIRON
Medical Subject Headings A0033410 AT199400104 An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
(CPTSP) CRISP Thesaurus A0475163 AT51224601 8-(4-(2-pyrimidinyl)-1-piperazinyl) butyl-8-azaspirodecane-7,9- dione; serotonergic tranquilizer frequently contrasted with benzodiazepine-type, GABAergic tranquilizers.
NCI NCI Dictionary of Cancer Terms A12796258 AT198008244 A drug that is used to treat certain anxiety disorders. It belongs to the family of drugs called antianxiety agents.
NCI Thesaurus A12796258 AT198131519 An anxiolytic agent chemically and pharmacologically unrelated to benzodiazepines, barbiturates, or other sedative/hypnotic drugs. Although its exact mechanism of action is unknown, buspirone may exert its anti-anxiety effects via serotonin (5-HT1A) and dopamine receptors (D2) and may indirectly affect other neurotransmitter systems. Unlike typical benzodiazepine anxiolytics, this agent does not exert anticonvulsant or muscle relaxant effects and lacks prominent sedative effects.