C0006976 - A broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Carbenicillin acylates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis.

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Lang Dictionary CODE			LUI	preferred no	SUI	preference Yes / No	Terms, descriptions
							CUI C0006976

Russian	Medical Subject Headings Russian	D002228	L3351534	preferred	S3879018	Y	КАРБЕНИЦИЛЛИН
Russian	Medical Subject Headings Russian	D002228	L0896256	no	S1100073	Y	KARBENITSILLIN
Russian	Medical Subject Headings Russian	D002228	L1525745	no	S1821654	Y	KARBOKSIBENZILPENITSILLIN
Russian	Medical Subject Headings Russian	D002228	L3351548	no	S3879030	Y	КАРБОКСИБЕНЗИЛПЕНИЦИЛЛИН
	Medical Subject Headings				A0034755	AT38154351	Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
	NCI Thesaurus				A7569319	AT198091065	A broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Carbenicillin acylates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis.