C0006982 - A hydrazine derivative of dopa. Carbidopa is a peripheral dopa decarboxylase inhibitor that is used as an adjunct to levodopa administration to prevent peripheral biosynthesis of levodopa to dopamine, thereby reducing peripheral side effects. Carbidopa does not penetrate the blood brain barrier so that levodopa, after it reaches the brain, can be metabolized to dopamine by dopa decarboxylase where it exerts its effect on dopamine receptors. 1/10
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Terms, descriptions
CUI    C0006982
RussianMedical Subject Headings Russian D002230 L3351538preferred S3879022 Y КАРБИДОФА
RussianMedical Subject Headings Russian D002230 L0896258no S1100075 Y KARBIDOFA
RussianMedical Subject Headings Russian D002230 L1530231no S1826140 Y METILDOFAGIDRAZIN
RussianMedical Subject Headings Russian D002230 L1530824no S1826733 Y MK-485
RussianMedical Subject Headings Russian D002230 L1530825no S1826734 Y MK-486
RussianMedical Subject Headings Russian D002230 L3357418no S3884903 Y МЕТИЛДОФАГИДРАЗИН
Medical Subject Headings A0034772 AT235448217 An inhibitor of DOPA DECARBOXYLASE that prevents conversion of LEVODOPA to dopamine. It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA. It has no anti-parkinson activity by itself.
NCI Thesaurus A10760303 AT198079906 A hydrazine derivative of dopa. Carbidopa is a peripheral dopa decarboxylase inhibitor that is used as an adjunct to levodopa administration to prevent peripheral biosynthesis of levodopa to dopamine, thereby reducing peripheral side effects. Carbidopa does not penetrate the blood brain barrier so that levodopa, after it reaches the brain, can be metabolized to dopamine by dopa decarboxylase where it exerts its effect on dopamine receptors.