C0008163 - An orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. (NCI04)

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Lang Dictionary CODE			LUI	preferred no	SUI	preference Yes / No	Terms, descriptions
							CUI C0008163

Russian	Medical Subject Headings Russian	D002699	L3375305	preferred	S3902797	Y	ХЛОРАМБУЦИЛ
Russian	Medical Subject Headings Russian	D002699	L0896614	no	S1100431	Y	KHLORAMBUTSIL
	Medical Subject Headings				A0037980	AT38149838	A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
	(CPTSP) CRISP Thesaurus				A0475933	AT51221836	nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others; may be a carcinogen.
	PDQ				A4343591	AT70662942	An orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43113&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43113&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C362" NCI Thesaurus)
	NCI NCI Dictionary of Cancer Terms				A7569510	AT198005103	A drug used to treat several types of leukemias and lymphomas. It blocks cell growth by damaging the cell's DNA and may kill cancer cells. It is a type of alkylating agent.
	NCI Thesaurus				A7569510	AT198054549	An orally-active antineoplastic aromatic nitrogen mustard. Chlorambucil alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. (NCI04)