C0012203 - A synthetic form of the hormone estrogen that was prescribed to pregnant women between about 1940 and 1971 because it was thought to prevent miscarriages. Diethylstilbestrol may increase the risk of uterine, ovarian, or breast cancer in women who took it. It also has been linked to an increased risk of clear cell carcinoma of the vagina or cervix in daughters exposed to diethylstilbestrol before birth. 1/10
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Terms, descriptions
CUI    C0012203
RussianMedical Subject Headings Russian D004054 L3348215preferred S3875694 Y ДИЭТИЛСТИЛЬБЭСТРОЛ
RussianMedical Subject Headings Russian D004054 L0892214no S1096031 Y DIETILSTIL'BESTROL
RussianMedical Subject Headings Russian D004054 L1543264no S1839173 Y STIL'BESTROL
RussianMedical Subject Headings Russian D004054 L3370593no S3898085 Y СТИЛЬБЭСТРОЛ
Medical Subject Headings A0048614 AT38136329 A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed)
(CPTSP) CRISP Thesaurus A0477776 AT51224096 synthetic nonsteroidal estrogen used in the treatment of menopausal, postmenopausal, and other disorders sensitive to estrogens; an epigenetic carcinogen.
PDQ A4343633 AT70646927 DES; the acronym for diethylstilbestrol, a synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, DES inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43081&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43081&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C433" NCI Thesaurus)
NCI Thesaurus A7570058 AT197980807 A synthetic, nonsteroidal form of estrogen. A well-known teratogen and carcinogen, diethylstilbestrol inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration.
NCI NCI Dictionary of Cancer Terms A7570058 AT198128995 A synthetic form of the hormone estrogen that was prescribed to pregnant women between about 1940 and 1971 because it was thought to prevent miscarriages. Diethylstilbestrol may increase the risk of uterine, ovarian, or breast cancer in women who took it. It also has been linked to an increased risk of clear cell carcinoma of the vagina or cervix in daughters exposed to diethylstilbestrol before birth.