C0018378 - A progressive autoimmune disorder of the peripheral nervous system characterized by respiratory insufficiency, limb paresthesias, areflexia, and generalized muscle weakness or paralysis that often begins in the legs and spreads to the arms, torso, and face. 1/10
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Terms, descriptions
CUI    C0018378
RussianMedical Subject Headings Russian D020275 L3345112preferred S3872591 Y ГИЙЕНА-БАРРЕ СИНДРОМ
RussianMedical Subject Headings Russian D020275 L1521586no S1817495 Y GIIENA-BARRE SINDROM
RussianMedical Subject Headings Russian D020275 L1533162no S1829071 Y NEVROPATIIA AUTOIMMUNNAIA OSTRAIA
RussianMedical Subject Headings Russian D020275 L1536776no S1832685 Y POLIRADIKULONEVROPATIIA DEMIELINIZIRUIUSHCHAIA VOSPALITEL'NAIA OSTRAIA
RussianMedical Subject Headings Russian D020275 L1536777no S1832686 Y POLIRADIKULONEVROPATIIA VOSPALITEL'NAIA OSTRAIA
RussianMDRRUS 10018766 L15740799no S19079324 Y Синдром Гийена-Барре (СГБ)
RussianMDRRUS 10018767 L15773859no S19079326 N Синдром Гийена-Барре
RussianMDRRUS 10042812 L15773859no S19079326 N Синдром Гийена-Барре
RussianMDRRUS 10018767 L15773859no S19079326 Y Синдром Гийена-Барре
RussianMedical Subject Headings Russian D020275 L3359566no S3887052 Y НЕВРОПАТИЯ АУТОИММУННАЯ ОСТРАЯ
RussianMedical Subject Headings Russian D020275 L3364403no S3891884 Y ПОЛИРАДИКУЛОНЕВРОПАТИЯ ВОСПАЛИТЕЛЬНАЯ ОСТРАЯ
RussianMedical Subject Headings Russian D020275 L3364404no S3891885 Y ПОЛИРАДИКУЛОНЕВРОПАТИЯ ДЕМИЕЛИНИЗИРУЮЩАЯ ВОСПАЛИТЕЛЬНАЯ ОСТРАЯ
Medical Subject Headings A0065286 AT38146220 An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)
(CPTSP) CRISP Thesaurus A1303682 AT51221429 progressive ascending motor neuron paralysis of unknown etiology, frequently following an enteric or respiratory infection.
Medical Subject Headings Czech A13039070 AT195259601 Zánětlivé onemocnění nervových kořenů, které se projevuje porušenou citlivostí a hybností končetin. Kromě míšních kořenů mohou být postiženy i hlavové nervy, popř. i další části CNS. Podle postižení a průběhu se rozlišují různé formy (např. ascendentní, descendentní, pseudomyopatická s nápadnými svalovými atrofiemi aj.). Vzniká sekundárně, předpokládá se, že patogeneticky se uplatňují autoimunitní procesy charakteru vaskulitidy v oblasti míšních kořenů. Obv. následuje po chřipkovém onemocnění či jiné infekci (např. při Lymeské borrelióze), které zřejmě chorobu iniciují. Po několika týdnech dochází většinou k uzdravení, jen někdy choroba postupuje dále a postihuje i dýchací svaly (Landryho vzestupná paralýza). Terapie je zaměřena imunosupresivně (kortikoidy, imunosupresiva, plasmaferéza), podávají se rovněž vitaminy skupiny B, významná je rehabilitace. Syn. polyradikuloneuritida. (cit. Velký lékařský slovník online, 2013 http://lekarske.slovniky.cz/ )
MEDLINEPLUS A21143438 AT203073164

Guillain-Barre syndrome is a rare disorder that causes your immune system to attack your peripheral nervous system (PNS). The PNS nerves connect your brain and spinal cord with the rest of your body. Damage to these nerves makes it hard for them to transmit signals. As a result, your muscles have trouble responding to your brain. No one knows what causes the syndrome. Sometimes it is triggered by an infection, surgery, or a vaccination.

The first symptom is usually weakness or a tingling feeling in your legs. The feeling can spread to your upper body. In severe cases, you become almost paralyzed. This is life-threatening. You might need a respirator to breathe. Symptoms usually worsen over a period of weeks and then stabilize.

Guillain-Barre can be hard to diagnose. Possible tests include nerve tests and a spinal tap. Most people recover. Recovery can take a few weeks to a few years. Treatment can help symptoms, and may include medicines or a procedure called plasma exchange.

NIH: National Institute of Neurological Disorders and Stroke

MSHNOR A24285375 AT221448527 En akutt inflammatorisk, autoimmun nevritt forårsaket av T-cellemediert cellulær immunrespons mot perifert myelin. Demyeliniseringen oppstår i perifere nerver og nerverøtter. Sykdomsprosessen starter ofte etter en viral eller bakteriell infeksjon, kirurgisk inngrep, immunisering, lymfom eller eksponering for giftstoffer. Vanlige kliniske manifestasjoner inkluderer tiltakende svakhet, tap av følelse og tap av dype senereflekser. Svekking av pustemuskulatur og autonom dysfunksjon kan forekomme.
NCI Thesaurus A24372014 AT205733670 A rapidly progressive autoimmune disorder of the peripheral nervous system characterized by limb paresthesias, areflexia, and generalized muscle weakness or paralysis that often begins in the legs and spreads to the arms, torso, and face.
NCI National Institute of Child Health and Human Development A24372014 AT210375479 A progressive autoimmune disorder of the peripheral nervous system characterized by respiratory insufficiency, limb paresthesias, areflexia, and generalized muscle weakness or paralysis that often begins in the legs and spreads to the arms, torso, and face.