C0025023 - A synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake. This results in a depletion of glycogen stores and leads to reduced formation of ATP required for survival and reproduction of the helminth. This eventually causes the helminths death.

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Lang Dictionary CODE			LUI	preferred no	SUI	preference Yes / No	Terms, descriptions
							CUI C0025023

Russian	Medical Subject Headings Russian	D008463	L3356582	preferred	S3884065	Y	МЕБЕНДАЗОЛ
Russian	Medical Subject Headings Russian	D008463	L0898710	no	S1102527	Y	MEBENDAZOL
Russian	Medical Subject Headings Russian	D008463	L1548284	no	S1844193	Y	VERMOKS
Russian	Medical Subject Headings Russian	D008463	L3342514	no	S3869996	Y	ВЕРМОКС
	Medical Subject Headings				A0083796	AT64676781	A benzimidazole that acts by interfering with CARBOHYDRATE METABOLISM and inhibiting polymerization of MICROTUBULES.
	NCI Thesaurus				A10761506	AT198141609	A synthetic benzimidazole derivate and anthelmintic agent. Mebendazole interferes with the reproduction and survival of helminths by inhibiting the formation of their cytoplasmic microtubules, thereby selectively and irreversibly blocking glucose uptake. This results in a depletion of glycogen stores and leads to reduced formation of ATP required for survival and reproduction of the helminth. This eventually causes the helminths death.