C0029456 - Reduced bone mineral density due to decreased number and thickness of bone trabeculae and decreased cortical thickness, associated with increased risk of skeletal fractures. A clinical diagnosis of osteoporosis in childhood requires either a finding of one or more otherwise unexplained vertebral compression fractures, or the presence of bone mineral density Z-score less than or equal to 2.0 accompanied by one or more of the following: 1) at least two long bone fractures by age 10 years; 2) at least three long bone fractures up to age 19 years.

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Lang Dictionary CODE			LUI	preferred no	SUI	preference Yes / No	Terms, descriptions
							CUI C0029456

Russian	Medical Subject Headings Russian	D010024	L3361818	preferred	S3889304	Y	ОСТЕОПОРОЗ
Russian	Medical Subject Headings Russian	D010024	L0901061	no	S1104878	Y	OSTEOPOROZ
Russian	Medical Subject Headings Russian	D010024	L1534762	no	S1830671	Y	OSTEOPOROZ STARCHESKII
Russian	MDRRUS	10031282	L15726841	no	S19056205	N	Остеопороз
Russian	MDRRUS	10031282	L15726841	no	S19056205	Y	Остеопороз
Russian	MDRRUS	10031284	L15737908	no	S19056201	Y	Остеопороз, БДУ
Russian	MDRRUS	10031289	L15792895	no	S19056203	Y	Остеопороз, неуточненный
Russian	Medical Subject Headings Russian	D010024	L3361822	no	S3889308	Y	ОСТЕОПОРОЗ СТАРЧЕСКИЙ
	Medical Subject Headings				A0095854	AT38141702	Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.
	(CPTSP) CRISP Thesaurus				A0485377	AT51222339	loss of bone mass and strength due to nutritional, metabolic, or other factors, usually resulting in deformity or fracture; a major public health problem of the elderly, especially women.
	Medical Subject Headings Czech				A13041854	AT211621372	Časté onemocnění charakterizované úbytkem kostní hmoty, "řídnutí kostí". Typ I je tzv. o. postmenopauzální (výrazně častější u žen, časté jsou fraktury obratlů a distálního předloktí, postižena je zejm. trabekulární kost), typ II je o. senilní (poměr žen k mužům je asi 2:1, frakturami je postižen skelet axiální i apendikulární, bývají zlomeniny krčku stehenní kosti, postižena je kost trabekulární i kortikální). Příčina není zcela jasná, vyskytuje se ve vyšším věku častěji u žen po přechodu nebo po odstranění vaječníků ještě v plodném období, bývá následkem dlouhodobé nehybnosti, delší léčby kortikoidy nebo důsledkem některých vzácnějších chorob. Vliv má kouření, nadměrná konzumace kávy aj. Projevuje se bolestmi (např. zad) a představuje vyšší riziko zlomeniny (krček stehenní kosti, kompresivní fraktura obratle). K diagnostice lze využít rentgenové vyšetření, osteodenzitometrii, biochemická vyšetření sledující kostní metabolismus. Léčba je dlouhodobá a může spíše jen zastavit další vývoj onemocnění. Uplatňují se kalcium, vitamin D, fluoridy, bisfosfonáty zejm. alendronát, kalcitonin, HRT, SERM, anabolika, symptomatická a fyzikální terapie; velký význam má rehabilitace (a přiměřené zatěžování kostí). Důležitá je prevence (dostatek vápníku, pohyb, u žen podávání pohlavních hormonů po - zejm. předčasném - přechodu, srov. HRT). (cit. Velký lékařský slovník online, 2013 http://lekarske.slovniky.cz/ )
	MEDLINEPLUS				A21144297	AT230153839	Osteoporosis is a disease that thins and weakens the bones. Your bones become fragile and break easily, especially the bones in the hip, spine, and wrist. In the United States, millions of people either already have osteoporosis or are at high risk due to low bone mass. Anyone can develop osteoporosis, but it is more common in older women. Risk factors include Getting older Being small and thin Having a family history of osteoporosis Taking certain medicines Being a white or Asian woman Having low bone density Osteoporosis is a silent disease. You might not know you have it until you break a bone. A bone mineral density test is the best way to check your bone health. To keep bones strong, eat a diet rich in calcium and vitamin D, exercise, and do not smoke. If needed, medicines can also help. It is also important to try to avoid falling down. Falls are the number one cause of fractures in older adults. NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases
	MSHNOR				A21182748	AT221393278	Reduksjon av mengden beinvev (tap av beinmasse), skjelettet blir porøst og risikoen for brudd øker. Primær osteoporose forkommer i to hovedtyper: postmenopausal osteoporose (beinskjørhet etter menopausen) og aldersrelatert eller senil osteoporose.
	HPO				A24666022	AT206301289	Osteoporosis is a systemic skeletal disease characterized by low bone density and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility. According to the WHO, osteoporosis is characterized by a value of BMD 2.5 standard deviations or more below the young adult mean. [HPO:curators]
	NCI Thesaurus				A7572722	AT197955175	A condition of reduced bone mass, with decreased cortical thickness and a decrease in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. Osteoporosis is classified as primary (Type 1, postmenopausal osteoporosis; Type 2, age-associated osteoporosis; and idiopathic, which can affect juveniles, premenopausal women, and middle-aged men) and secondary osteoporosis (which results from an identifiable cause of bone mass loss).
	NCI NCI Dictionary of Cancer Terms				A7572722	AT198004922	A condition that is marked by a decrease in bone mass and density, causing bones to become fragile.
	NCI Common Terminology Criteria for Adverse Events				A7572722	AT198017348	A disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence.
	NCI National Institute of Child Health and Human Development				A7572722	AT224186328	Reduced bone mineral density due to decreased number and thickness of bone trabeculae and decreased cortical thickness, associated with increased risk of skeletal fractures. A clinical diagnosis of osteoporosis in childhood requires either a finding of one or more otherwise unexplained vertebral compression fractures, or the presence of bone mineral density Z-score less than or equal to 2.0 accompanied by one or more of the following: 1) at least two long bone fractures by age 10 years; 2) at least three long bone fractures up to age 19 years.