Classification Nuance. The OpenFDA dataset, which draws from the Structured Product Labeling (SPL) files, often includes multiple classification fields, and the specific string "Phosphate Binder [EPC]" may only be assigned to a single product. The other drugs are likely classified using: More Specific Classes: Many of those drugs (like sevelamer, ferric citrate, etc.) may be classified by their specific mechanism or chemical group, which also acts as a phosphate binder. Example: A drug might be classified as "Iron-Containing Compound [EPC]" or "Aluminum-Containing Compound [EPC]" instead of the more general "Phosphate Binder [EPC]". Different Classification Fields: The NDC data contains several classification fields. You might be checking the Established Pharmacological Class (pharm_class_epc), but the other drugs might be listed under: Mechanism of Action (pharm_class_moa), Physiological Effect (pharm_class_pe)
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Central alpha-2 Adrenergic Agonist [EPC]

NDC Number Brand Name Generic Name Manufacturer Dosage Form DEA Sch. Marketing Start Date
0378-0871 Clonidine clonidine Mylan Pharmaceuticals Inc. PATCH 2013-02-25
0378-0872 Clonidine clonidine Mylan Pharmaceuticals Inc. PATCH 2013-03-04
0378-0873 Clonidine clonidine Mylan Pharmaceuticals Inc. PATCH 2013-03-01
0591-3508 Clonidine transdermal system Clonidine Actavis Pharma, Inc. PATCH 2014-05-06
0591-3509 Clonidine transdermal system Clonidine Actavis Pharma, Inc. PATCH 2014-05-06
0591-3510 Clonidine transdermal system Clonidine Actavis Pharma, Inc. PATCH 2014-05-06
24979-533 Guanfacine Extended-Release Guanfacine Upsher-Smith Laboratories, LLC TABLET, EXTENDED RELEASE 2017-07-07
24979-534 Guanfacine Extended-Release Guanfacine Upsher-Smith Laboratories, LLC TABLET, EXTENDED RELEASE 2017-07-07
24979-536 Guanfacine Extended-Release Guanfacine Upsher-Smith Laboratories, LLC TABLET, EXTENDED RELEASE 2017-07-07
24979-538 Guanfacine Extended-Release Guanfacine Upsher-Smith Laboratories, LLC TABLET, EXTENDED RELEASE 2017-07-07
29300-458 Guanfacine Hydrochloride Guanfacine Hydrochloride Unichem Pharmaceuticals (USA), Inc. TABLET 2021-03-03
29300-459 Guanfacine Hydrochloride Guanfacine Hydrochloride Unichem Pharmaceuticals (USA), Inc. TABLET 2021-03-03
51862-455 Clonidine CLONIDINE Mayne Pharma Inc. PATCH, EXTENDED RELEASE 2016-08-03
52817-375 Clonidine Clonidine TruPharma, LLC TABLET, EXTENDED RELEASE 2024-01-11
52817-610 Clonidine Transdermal System USP, 0.1 mg/day clonidine transdermal system TruPharma, LLC PATCH 2023-06-30
52817-611 Clonidine Transdermal System USP, 0.2 mg/day clonidine transdermal system TruPharma, LLC PATCH 2023-06-30
52817-612 Clonidine Transdermal System USP, 0.3 mg/day clonidine transdermal system TruPharma, LLC PATCH 2023-06-30
60429-960 Guanfacine Extended-Release Guanfacine Golden State Medical Supply, Inc. TABLET, EXTENDED RELEASE 2015-06-02
60429-961 Guanfacine Extended-Release Guanfacine Golden State Medical Supply, Inc. TABLET, EXTENDED RELEASE 2015-06-02
60429-962 Guanfacine Extended-Release Guanfacine Golden State Medical Supply, Inc. TABLET, EXTENDED RELEASE 2015-06-02
60429-963 Guanfacine Extended-Release Guanfacine Golden State Medical Supply, Inc. TABLET, EXTENDED RELEASE 2015-06-02
60687-710 Guanfacine Hydrochloride Guanfacine Hydrochloride American Health Packaging TABLET 2023-11-09
68134-603 Clonidine Clonidine PALMETTO PHARMACEUTICALS INC. TABLET, EXTENDED RELEASE 2022-03-01
70518-2771 Guanfacine Extended-Release Guanfacine REMEDYREPACK INC. TABLET, EXTENDED RELEASE 2020-06-08
70518-3516 Guanfacine Hydrochloride Guanfacine Hydrochloride REMEDYREPACK INC. TABLET 2022-09-13
70518-3809 Guanfacine Extended-Release Guanfacine REMEDYREPACK INC. TABLET, EXTENDED RELEASE 2023-07-29
71205-944 Guanfacine Extended-Release Guanfacine Proficient Rx LP TABLET, EXTENDED RELEASE 2017-07-07
71205-945 Guanfacine Extended-Release Guanfacine Proficient Rx LP TABLET, EXTENDED RELEASE 2017-07-07
71205-946 Guanfacine Extended-Release Guanfacine Proficient Rx LP TABLET, EXTENDED RELEASE 2017-07-07
71205-947 Guanfacine Extended-Release Guanfacine Proficient Rx LP TABLET, EXTENDED RELEASE 2017-07-07
71511-503 Nexiclon XR Clonidine Athena Bioscience, LLC TABLET, EXTENDED RELEASE 2022-03-01
75907-023 Clonidine CLONIDINE Dr. Reddy's Labratories Inc. PATCH, EXTENDED RELEASE 2024-02-10
75907-024 Clonidine CLONIDINE Dr. Reddy's Labratories Inc. PATCH, EXTENDED RELEASE 2024-02-10
75907-025 Clonidine CLONIDINE Dr. Reddy's Labratories Inc. PATCH, EXTENDED RELEASE 2024-02-10
81092-1120 IGALMI DEXMEDETOMIDINE BioXcel Therapeutics, Inc. FILM 2022-07-01
81092-1180 IGALMI DEXMEDETOMIDINE BioXcel Therapeutics, Inc. FILM 2022-07-01
82089-101 Catapres-TTS-1 clonidine transdermal system Technomed Inc. PATCH 2022-03-01
82089-102 Catapres-TTS-2 clonidine transdermal system Technomed Inc. PATCH 2022-03-01
82089-103 Catapres-TTS-3 clonidine transdermal system Technomed Inc. PATCH 2022-03-01



 [EPC] Established Pharmacological Classification 

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