Classification Nuance. The OpenFDA dataset, which draws from the Structured Product Labeling (SPL) files, often includes multiple classification fields, and the specific string "Phosphate Binder [EPC]" may only be assigned to a single product. The other drugs are likely classified using: More Specific Classes: Many of those drugs (like sevelamer, ferric citrate, etc.) may be classified by their specific mechanism or chemical group, which also acts as a phosphate binder. Example: A drug might be classified as "Iron-Containing Compound [EPC]" or "Aluminum-Containing Compound [EPC]" instead of the more general "Phosphate Binder [EPC]". Different Classification Fields: The NDC data contains several classification fields. You might be checking the Established Pharmacological Class (pharm_class_epc), but the other drugs might be listed under: Mechanism of Action (pharm_class_moa), Physiological Effect (pharm_class_pe)
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Endoglycosidase [EPC]

NDC Number Brand Name Generic Name Manufacturer Dosage Form DEA Sch. Marketing Start Date
0003-6120 OPDIVO QVANTIG nivolumab and hyaluronidase-nvhy E.R. Squibb & Sons, L.L.C. INJECTION, SOLUTION 2025-01-02
0548-9090 AMPHADASE hyaluronidase Amphastar Pharmaceuticals, Inc. INJECTION 2004-10-26
17089-416 GUNA-MATRIX ASCORBIC ACID - DODECAHYDROXYCYCLOHEXANE DIHYDRATE - FUCUS VESICULOSUS - HISTIDINE MONOHYDROCHLORIDE - HUMAN INTERLEUKIN-6 (NONGLYCOSYLATED) - HYALURONIDASE - LACTIC ACID, DL - MALIC ACID - NADIDE - PHENYLALANINE - PRASTERONE - PROLACTIN - RANCID BEEF - SODIUM DIETHYL OXALACETATE - SODIUM PYRUVATE - SODIUM SULFATE - SUS SCROFA CONJUNCTIVA - SUS SCROFA SMALL INTESTINE MUCOSA LYMPH FOLLICLE - THUJA OCCIDENTALIS TWIG - TYROSINE - Guna spa SOLUTION/ DROPS 2010-05-27
18657-117 HYLENEX Recombinant Hyaluronidase Antares Pharma, Inc. INJECTION, SOLUTION 2005-12-02
43742-1548 Pest and Dustmite Formula Amyl Nitrosum, Euphrasia Officinalis, Kali Muriaticum, Wyethia Helenoides, Histaminum Hydrochloricum, Lac Caninum, Glandula Suprarenalis Suis, Mucosa Nasalis Suis, Allium Cepa, Arsenicum Album, Blatta Americana, Iridium Metallicum, Sabadilla, Selenium Metallicum, Lac Felinum, Hyaluronidase, Interferon (Suis), Serotonin (Hydrochloride), House Dust Mite Deseret Biologicals, Inc. LIQUID 2019-09-19
43742-1950 Enviro I Potassium Gluconate, Glandula Suprarenalis Suis, Hepar Suis, Coffea Tosta, Thea Sinensis, Carbo Vegetabilis, Ferrum Iodatum, Ferrum Metallicum, Gelsemium Sempervirens, Iodium, Iridium Metallicum, Lycopodium Clavatum, Pulsatilla (Pratensis), Selenium Metallicum, Zincum Metallicum, Peanut, Black Walnut, English Walnut, Amygdala Amara, Cashew, Coconut, Pecan, Brazil Nut, Tomato, Solanum Tuberosum, Piper Nigrum, Eggplant, Rape Seed Oil, Linum Usitatissimum, Sesame, Seed, Cheese (Stilton), Lac Vaccinum, Beef, Deseret Biologicals, Inc. LIQUID 2021-02-26
50090-4534 HYLENEX Recombinant Hyaluronidase (Human Recombinant) A-S Medication Solutions INJECTION, SOLUTION 2005-12-02
50242-077 Herceptin Hylecta Trastuzumab and hyaluronidase-oysk Genentech, Inc. INJECTION, SOLUTION 2019-02-28
50242-108 Rituxan Hycela rituximab and hyaluronidase Genentech, Inc. INJECTION, SOLUTION 2017-06-22
50242-109 Rituxan Hycela rituximab and hyaluronidase Genentech, Inc. INJECTION, SOLUTION 2017-06-22
50242-245 Phesgo pertuzumab, trastuzumab, and hyaluronidase-zzxf Genentech, Inc. INJECTION, SOLUTION 2020-06-29
50242-260 Phesgo pertuzumab, trastuzumab, and hyaluronidase-zzxf Genentech, Inc. INJECTION, SOLUTION 2020-06-29
50242-554 Ocrevus Zunovo ocrelizumab and hyaluronidase Genentech, Inc. INJECTION, SOLUTION 2024-09-13
50242-933 Tecentriq Hybreza atezolizumab and hyaluronidase-tqjs Genentech, Inc. INJECTION 2024-09-12
51662-1555 HYALURONIDASE HYALURONIDASE HF Acquisition Co LLC, DBA HealthFirst INJECTION, SOLUTION 2021-06-04
57894-503 Darzalex Faspro daratumumab and hyaluronidase-fihj (human recombinant) Janssen Biotech, Inc. INJECTION 2020-05-01
73475-1221 VYVGART Hytrulo efgartigimod alfa and hyaluronidase (human recombinant) argenx US INJECTION, SOLUTION 2025-04-10
73475-3102 VYVGART Hytrulo efgartigimod alfa and hyaluronidase (human recombinant) argenx US INJECTION, SOLUTION 2023-06-20



 [EPC] Established Pharmacological Classification 

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