Classification Nuance. The OpenFDA dataset, which draws from the Structured Product Labeling (SPL) files, often includes multiple classification fields, and the specific string "Phosphate Binder [EPC]" may only be assigned to a single product. The other drugs are likely classified using: More Specific Classes: Many of those drugs (like sevelamer, ferric citrate, etc.) may be classified by their specific mechanism or chemical group, which also acts as a phosphate binder. Example: A drug might be classified as "Iron-Containing Compound [EPC]" or "Aluminum-Containing Compound [EPC]" instead of the more general "Phosphate Binder [EPC]". Different Classification Fields: The NDC data contains several classification fields. You might be checking the Established Pharmacological Class (pharm_class_epc), but the other drugs might be listed under: Mechanism of Action (pharm_class_moa), Physiological Effect (pharm_class_pe)
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Histamine-1 Receptor Antagonist [EPC]

NDC Number Brand Name Generic Name Manufacturer Dosage Form DEA Sch. Marketing Start Date
0023-4290 LASTACAFT alcaftadine Allergan, Inc. SOLUTION/ DROPS 2010-11-01
0023-4291 LASTACAFT alcaftadine Allergan, Inc. SOLUTION/ DROPS 2021-12-01
0363-9661 Acetaminophen Diphenhydramine HCL Acetaminophen Diphenhydramine HCL Walgreens TABLET 2024-06-23
21130-661 Acetaminophen and Diphenhydramine HCL Acetaminophen and Diphenhydramine HCL SAFEWAY TABLET 2023-06-30
37835-537 Acetaminophen and Diphenhydramine Hydrochloride Acetaminophen and Diphenhydramine Hydrochloride Bi-Mart TABLET 2025-02-01
41415-661 Acetaminophen and Diphenhydramine HCL Acetaminophen and Diphenhydramine HCL PUBLIX SUPERMARKETS, INC TABLET 2024-08-02
50090-3975 Desloratadine Desloratadine A-S Medication Solutions TABLET 2015-06-12
50090-4794 DESLORATADINE DESLORATADINE A-S Medication Solutions TABLET, FILM COATED 2013-02-25
50090-6724 DESLORATADINE DESLORATADINE A-S Medication Solutions TABLET, FILM COATED 2013-02-25
55111-360 Desloratadine Desloratadine Dr. Reddy's Laboratories Limited TABLET, ORALLY DISINTEGRATING 2013-01-11
55111-551 Desloratadine Desloratadine Dr. Reddy's Laboratories Limited TABLET, ORALLY DISINTEGRATING 2013-01-11
58602-605 Alcaftadine Alcaftadine Aurohealth LLC SOLUTION/ DROPS 2023-06-23
62332-147 alcaftadine alcaftadine Alembic Pharmaceuticals Inc. SOLUTION/ DROPS 2024-10-02
63029-054 Percogesic Extra Strength acetaminophen and diphenhydramine Medtech Products Inc. CAPSULE, COATED 2010-07-07
67234-023 Dermamine Extra Strength Itch Stopping DIPHENHYDRAMINE and ZINC ACETATE Natureplex LLC CREAM 2014-03-01
68016-654 Acetaminophen Diphenhydramine HCl Acetaminophen Diphenhydramine HCl Chain Drug Consortium,LLC TABLET 2016-02-25
68083-649 Alcaftadine Alcaftadine Gland Pharma Limited SOLUTION/ DROPS 2024-03-01
68180-153 DESLORATADINE DESLORATADINE Lupin Pharmaceuticals, Inc. TABLET, FILM COATED 2013-02-25
69452-363 Desloratadine Desloratadine Bionpharma Inc. TABLET, FILM COATED 2023-11-28
69543-107 Desloratadine Desloratadine Virtus Pharmaceuticals, LLC TABLET 2015-06-12
71335-1000 DESLORATADINE DESLORATADINE Bryant Ranch Prepack TABLET, FILM COATED 2013-02-25
72162-2308 Desloratadine Desloratadine Bryant Ranch Prepack TABLET 2015-06-12
78206-119 Clarinex Desloratadine Organon LLC TABLET, FILM COATED 2021-06-01
78206-120 CLARINEX-D 12 HOUR desloratadine and pseudoephedrine sulfate Organon LLC TABLET, EXTENDED RELEASE 2021-06-01
78206-188 Clarinex Desloratadine Organon LLC TABLET, FILM COATED 2022-08-23
82568-0016 DIPHENHYDRAMINE HCL 12.5 MG PER 5 ML DIPHENHYDRAMINE HCL 12.5 MG PER 5 ML AARNA USA INC. SOLUTION 2025-04-14
82667-015 ZERVIATE cetirizine Harrow Eye, LLC FOR SOLUTION 2025-04-30



 [EPC] Established Pharmacological Classification 

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