Classification Nuance. The OpenFDA dataset, which draws from the Structured Product Labeling (SPL) files, often includes multiple classification fields, and the specific string "Phosphate Binder [EPC]" may only be assigned to a single product. The other drugs are likely classified using: More Specific Classes: Many of those drugs (like sevelamer, ferric citrate, etc.) may be classified by their specific mechanism or chemical group, which also acts as a phosphate binder. Example: A drug might be classified as "Iron-Containing Compound [EPC]" or "Aluminum-Containing Compound [EPC]" instead of the more general "Phosphate Binder [EPC]". Different Classification Fields: The NDC data contains several classification fields. You might be checking the Established Pharmacological Class (pharm_class_epc), but the other drugs might be listed under: Mechanism of Action (pharm_class_moa), Physiological Effect (pharm_class_pe)
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Topoisomerase Inhibitor [EPC]

NDC Number Brand Name Generic Name Manufacturer Dosage Form DEA Sch. Marketing Start Date
0143-9376 Etoposide Etoposide Hikma Pharmaceuticals USA Inc. INJECTION 1996-05-01
0143-9510 Etoposide Etoposide Hikma Pharmaceuticals USA Inc. INJECTION 1996-05-01
0143-9511 Etoposide Etoposide Hikma Pharmaceuticals USA Inc. INJECTION 1997-02-01
0143-9512 Etoposide Etoposide Hikma Pharmaceuticals USA Inc. INJECTION 1997-02-01
0378-3266 Etoposide etoposide Mylan Pharmaceuticals Inc. CAPSULE 2001-10-22
16729-114 Etoposide Etoposide Accord Healthcare Inc. INJECTION 2015-03-03
16729-243 Topotecan Topotecan Accord Healthcare Inc. INJECTION 2020-07-08
63323-104 Etoposide ETOPOSIDE Fresenius Kabi USA, LLC INJECTION, SOLUTION 2001-07-18
68001-265 Etoposide Etoposide BluePoint Laboratories INJECTION 2013-11-14
68727-745 VYXEOS (daunorubicin and cytarabine) liposome Jazz Pharmaceuticals, Inc. INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 2017-08-03
71288-175 Etoposide Etoposide Meitheal Pharmaceuticals Inc. INJECTION, SOLUTION, CONCENTRATE 2025-02-01
71288-176 Etoposide Etoposide Meitheal Pharmaceuticals Inc. INJECTION, SOLUTION, CONCENTRATE 2025-02-01
71288-177 Etoposide Etoposide Meitheal Pharmaceuticals Inc. INJECTION, SOLUTION, CONCENTRATE 2025-02-01



 [EPC] Established Pharmacological Classification 

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