C0001403 - The diminished production of adrenocortical hormones due to a pathologic process within the adrenal glands. 4/10
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Terms, descriptions
CUI    C0001403
RussianMedical Subject Headings Russian D000224 L3336992preferred S3864473 Y АДДИСОНОВА БОЛЕЗНЬ
RussianMedical Subject Headings Russian D000224 L0889403no S1093220 Y ADDISONOVA BOLEZN'
RussianMedical Subject Headings Russian D000224 L1512013no S1807922 Y BRONZOVAIA BOLEZN'
RussianMDRRUS 10001130 L15755655no S19020931 N Болезнь Аддисона
RussianMDRRUS 10013096 L15755655no S19020931 N Болезнь Аддисона
RussianMDRRUS 10001130 L15755655no S19020931 Y Болезнь Аддисона
RussianMDRRUS 10052381 L15760952no S19062878 N Первичная надпочечниковая недостаточность
RussianMDRRUS 10052381 L15760952no S19062878 Y Первичная надпочечниковая недостаточность
RussianMDRRUS 10036696 L15771869no S19062939 Y Первичный гипоадренализм
RussianMedical Subject Headings Russian D000224 L3341917no S3869399 Y БРОНЗОВАЯ БОЛЕЗНЬ
(CPTSP) CRISP Thesaurus A0388277 AT51219985 disease characterized by hypotension, weight loss, anorexia, weakness, and sometimes a bronze-like melanotic hyperpigmentation of the skin; due to tuberculosis or autoimmune induced disease (hypofunction) of the adrenal glands that results in deficiency of aldosterone and cortisol.
Medical Subject Headings Czech A13061502 AT231357607 Onemocnění nadledvin charakterizované progresivní destrukcí kůry nadledvin, která se projevuje nedostatečnou tvorbou aldosteronu a kortizolu. Mezi klinické projevy patří anorexie, nauzea, hmotnostní úbytek, svalová slabost a hyperpigmentace kůže způsobená zvýšenou hladinou cirkulujícího prekurzoru ACTH, který stimuluje melanocyty.
MEDLINEPLUS A23169973 AT203073080

Your adrenal glands are just above your kidneys. The outside layer of these glands makes hormones that help your body respond to stress and regulate your blood pressure and water and salt balance. Addison disease happens if the adrenal glands don't make enough of these hormones.

A problem with your immune system usually causes Addison disease. The immune system mistakenly attacks your own tissues, damaging your adrenal glands. Other causes include infections and cancer.

Symptoms include

  • Weight loss
  • Muscle weakness
  • Fatigue that gets worse over time
  • Low blood pressure
  • Patchy or dark skin

Lab tests can confirm that you have Addison disease. If you don't treat it, it can be fatal. You will need to take hormone pills for the rest of your life. If you have Addison disease, you should carry an emergency ID. It should say that you have the disease, list your medicines and say how much you need in an emergency.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

HPO A24682993 AT206284062 Insufficient production of steroid hormones (primarily cortisol) by the adrenal glands as a result of a primary defect in the glands themselves. [HPO:probinson]
Medical Subject Headings A6954527 AT43116350 An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.
NCI Thesaurus A7568543 AT197991938 A long-standing and persistent diminished production of adrenocortical hormones due to a disorder originating within the adrenal glands.
NCI National Institute of Child Health and Human Development A7568543 AT224194322 The diminished production of adrenocortical hormones due to a pathologic process within the adrenal glands.