C0002575 - A methylxanthine and derivative of theophylline. Aminophylline relaxes smooth muscles, particularly bronchial muscles. This xanthine most likely exerts its effect by inhibiting cAMP or cGMP phosphodiesterases, thereby increasing levels of the second messenger cAMP or cGMP intracellularly. Other mode of actions include an adenosine antagonistic effect on the activity of CD4 lymphocytes and mediator release from mast cells thereby decreasing lung sensitivity to allergens and other substances that cause inflammation. Aminophylline also acts as a CNS stimulant and exerts a positive chronotropic and inotropic effect on the heart. 1/10
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Terms, descriptions
CUI    C0002575
RussianMedical Subject Headings Russian D000628 L3378572preferred S3906065 Y ЭУФИЛЛИН
RussianMedical Subject Headings Russian D000628 L0893301no S1097118 Y EUFILLIN
RussianMedical Subject Headings Russian D000628 L1508348no S1804257 Y AMINOFILLIN
RussianMedical Subject Headings Russian D000628 L3338153no S3865634 Y АМИНОФИЛЛИН
Medical Subject Headings A0013939 AT38138602 A drug combination that contains THEOPHYLLINE and ethylenediamine. It is more soluble in water than theophylline but has similar pharmacologic actions. It's most common use is in bronchial asthma, but it has been investigated for several other applications.
(CPTSP) CRISP Thesaurus A0473448 AT51221558 drug combination that contains theophylline and ethylenediamine; its most common use is in bronchial asthma, but it has been investigated for several other applications.
NCI Thesaurus A10759777 AT198104526 A methylxanthine and derivative of theophylline. Aminophylline relaxes smooth muscles, particularly bronchial muscles. This xanthine most likely exerts its effect by inhibiting cAMP or cGMP phosphodiesterases, thereby increasing levels of the second messenger cAMP or cGMP intracellularly. Other mode of actions include an adenosine antagonistic effect on the activity of CD4 lymphocytes and mediator release from mast cells thereby decreasing lung sensitivity to allergens and other substances that cause inflammation. Aminophylline also acts as a CNS stimulant and exerts a positive chronotropic and inotropic effect on the heart.