C0002679 - A polyene antifungal antibiotic produced by Streptomyces nodosus, with antifungal activity. Amphotericin B binds to ergosterol, an essential component of the fungal cell membrane, thereby causing depolarization of the membrane and altering cell membrane permeability. This leads to leakage of important intracellular components, cell rupture, and eventually cell death. This agent may also induce oxidative damage in fungal cells and has been reported to stimulate host immune cells.

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Lang Dictionary CODE			LUI	preferred no	SUI	preference Yes / No	Terms, descriptions
							CUI C0002679

Russian	Medical Subject Headings Russian	D000666	L15164857	preferred	S18459464	Y	АМФОТЕРИЦИН B
Russian	Medical Subject Headings Russian	D000666	L15157699	no	S18431873	Y	AMFOTERITSIN B
	Medical Subject Headings				A0023112	AT38149687	Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.
	(CPTSP) CRISP Thesaurus				A0473489	AT51220268	macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.
	NCI NCI Dictionary of Cancer Terms				A12783589	AT198077935	A drug used in the treatment of infections caused by fungi. It is a type of antifungal.
	NCI Thesaurus				A12783589	AT198090111	A polyene antifungal antibiotic produced by Streptomyces nodosus, with antifungal activity. Amphotericin B binds to ergosterol, an essential component of the fungal cell membrane, thereby causing depolarization of the membrane and altering cell membrane permeability. This leads to leakage of important intracellular components, cell rupture, and eventually cell death. This agent may also induce oxidative damage in fungal cells and has been reported to stimulate host immune cells.